Fig. 2. Apoptotic and anti-apoptotic proteins in myocardial infarction. A. Representative section from the LV of GAL-3 wild MI group at 24-hour following MI showing cytoplasmic expression of Bcl2 by cardiomyocytes in the ischemic area (thin arrow). B. Representative section from the LV of GAL-3 KO MI group at 24-hour following MI showing cytoplasmic expression of Bcl2 by cardiomyocytes in the ischemic area (thin arrow). C. A morphometric graph showing a significantly higher number of cells expressing Bcl2 in the LV of GAL-3 wild MI group than GAL-3 KO MI group. D. Representative section from the LV of GAL-3 wild MI group at 24-hour following MI showing cytoplasmic expression of cytochrome c by cardiomyocytes in the ischemic area (thin arrow). E. Representative section from the LV of GAL-3 KO MI group at 24-hour following MI showing cytoplasmic expression of cytochrome c by cardiomyocytes in the ischemic area (thin arrow). F. A morphometric graph showing a significantly higher number of cells expressing cytochrome c in the LV of GAL-3 KO MI group than GAL-3 wild MI group. G. Representative section from the LV of GAL-3 wild MI group at 24h following MI showing cytoplasmic expression of Bax protein by cardiomyocytes in the ischemic area (thin arrow). H. Representative section from the LV of GAL-3 KO MI group at 24-hour following MI showing cytoplasmic expression of Bax protein by cardiomyocytes in the ischemic area (thin arrow). I. A morphometric graph showing a significantly higher number of cells expressing Bax protein in the LV of GAL-3 KO MI group than GAL-3 wild MI group. J. Representative section from the LV of GAL-3 wild MI group at 24-hour following MI showing cytoplasmic and nuclear expression of cleaved caspase-3 protein by apoptotic cells in the ischemic area (thin arrow). K. Representative section from the LV of GAL-3 KO MI group at 24-hour following MI showing cytoplasmic and nuclear expression of cleaved caspase-3 protein by apoptotic cells in the ischemic area (thin arrow). L. A morphometric graph showing a significantly higher number of cells expressing cleaved caspase-3 protein in the LV of GAL-3 KO MI group than GAL-3 wild MI group. M. Representative section from the LV of GAL-3 wild MI group at 24-hour following MI showing membranous expression of annexin V protein by apoptotic cells in the ischemic area (thin arrow). N. Representative section from the LV of GAL-3 KO MI group at 24-hour following MI showing membranous expression of annexin V protein by apoptotic cells in the ischemic area (thin arrow). O. A morphometric graph showing a significantly higher number of cells expressing Annexin V protein in the LV of GAL-3 KO MI group than GAL-3 wild MI group. Note: P value<0.05 is statistically significant.